Causes

1. Secretory defects: Bile, pancreas
2. Motility / bacteria: DM, Infections.
3. Mucosal damage: Sprue, Whipple

Clinical Features

mainly due to fat malabsorption. not much absorbed, quantity increases, secondary infection, wall growth of gut bacteria

1. Chronic diarrhoea
2. Wt. loss, anorexia, bloating (from fermentation)
3. Steatorrhea – pale, greasy stools
4. Vit-D (hypocalcaemia → hyperparathyroidism in chronic) & Vit K deficiency (bleeding in chronic). (fat soluble ADEK deficiencey)

• Ileum and reabsorption of bile acids

Coeliac Disease / Gluten Sensitive Enteropathy

Tropical Sprue/ Environmental Enteropathy

Whipple’s Disease

Parasitic Infestation (Giardiasis)