Aetiology

Unknown cause

1. Poor hygiene
2. Feco-oral recurrent infections
3. Intestinal Inflammation
4. Immune activation
5. Enteropathy
6. Malabsorption
7. Malnutrition
8. infection due to malnutrition

Pathophysiology

unknown immune activation → atrophy of villi/mucosal atrophy and inflammation → malabsorption

Risk Factors

• Tropical
• Poor sanitation / hygiene.

Clinical Features