inflammation of brain parenchyma associated with neruo dysfunction

can be classified acording to location

<aside> 💡 fever, focal neuro, AMS

</aside>

Demographics: <20yo, >50yo

Aetiology:

• viral most common. HSV1 in adults, HSV2 in neonates, jap encephalitis, EBV, enteroviridae, rubella, mumps, measles, CMV
• bacterial: treponema pallidum, listeria
• fungal: cryptococcus neo
• Parasitic: N. fowleri, plasmodium, toxoplasma
• Autoimmune: anti NMDAR antibodies (assoc with paraneoplastic and ovarian teratoma)

Risk Factors

• Immunosuppression
• animal exposure
• travel to endemic areas (africa and asia)
• season (infecious common summer and spring)
• genetic predisposition