1. important health problem
2. recognisable latent or early symptomatic stage
3. natural history of disease adequately understood
4. accepted treatment for disease
5. suitable test with high accuracy
6. test is acceptable to population
7. agreed upon policy on who to treat
8. facilities for diagnosis and treatment should be available
9. cost of screening should be balanced with whole of medical care
10. screening should be continuous process not one and done