functions

• Thermoregulation
• Protective Barrier and Repair
• Sensation
• Immunologic protection
• Vitamin D synthesis
• Psychological and Communication effect through appearance with significant functional disability caused by skin disease

Structure

• Epidermis
• Dermis
• Hypodermis: composed of adipose tissue, blood and Lymph vessels and nerve

Sensory receptors

• Free nerve endings
• Merkel cell associated
• Encapsulated receptors: Pacinian and Meissner’s corpuscle