aka acetominophen

Desired Effect

• Anti-pyretic and analgesic (centrally acting) effects.
• NO anti-inflammatory effects.
• Note: Paracetamol is NOT a NSAID.

MOA

• Not fully determined.
• Mechanisms involved in its analgesic effect may include inhibition of central prostaglandin synthesis and modulation of inhibitory descending serotonergic pathways.
• The antipyretic effect is probably due to reduced production of prostaglandins in the hypothalamus.

Indication

1. Mild to moderate pain.
2. Fever.

Contraindication/precaution

Precautions for people with:

• Phenylketonuria
• On a sodium restricted diet.