OA

• Old age, Large joints
• Degenerative / Progressive
• Cartilage degeneration.
• Cartilage → Synovium
• Shorter Morning stiffness & crepitus, increases with activity.
• no ankylosis (typically, but osteophytes)

RA

• Young, small joints
• Autoimmune / recurrent
• Synovial Inflammation
• Synovium → Cartilage
• Prolonged Morning stiffness & Pain. reduce with activity (early stage)
• ankylosis