AKA Systemic menopausal hormone therapy (MHT)

Indications

Contraindications

DON’T choose Oestrogen Only UNLESS total hysterectomy

for all:

A personal history of breast cancer is a contraindication to systemic MHT because of the potential to promote recurrence.

• age 60 years or older
• previous venous thromboembolism
• previous transient ischaemic attack, stroke or acute myocardial infarction
• uncontrolled hypertension
• estrogen-dependent cancer (eg endometrial or breast cancer)
• undiagnosed vaginal bleeding (may indicate estrogen-dependent cancer)
• high risk of breast cancer
• significant liver disease
• porphyria or SLE (may be exacerbated by estrogen).