clexane, enxoparin

• MoA: inactivate FXa > FIIa
• Indications: prevent + Rx thromboembolism
• Contraindications: severe thrombocytopaenia, active bleeding, hepatic impairment
• Route/freq: subcut daily or bd
• Desired effect: can use in pregnancy, takes longer than heparin.
• Side effect: thrombocytopaenia, hypersensitivity, hyperkalaemia
• Reversibility: protamine sulphate