• Hypometabolism:

  • Weight gain, Apathy, Constipation, weakness

• marked accumulation of subcutaneous proteinous fluid (non pitting oedema)

• tibial Myxoedema

Commonest Cause

1. Primary, Autoimmune destruction of thyroid (Hashimoto’s)
2. Iodine deficiency

Hashimoto Thyroiditis

Cretinism