Epidemiology:

• Common in > 40
• Female > Male

Etiology/risk factors:

• Environmental: dry room air, smoke, working at computer screens
• Often associated with blepharitis
• Primary and secondary Sjogren's syndrome
• Disorders of lid positioning or decreased blink rate
• Medication: estrogen, antihistamine, anticholinergics, amiodarone
• Vitamin A deficiency
• Contact lenses

Clinical Features:

• Dry eyes
• Blurred vision
• Entropion or ectropion
• General signs and symptoms of conjunctivitis