• most common is Adenocarcinoma of colon.
• Small intestine neoplasms very rare!
• Second most common cancer in developed countries (lung), 1 in 20 people (60-80yo)
• Rare in the developing world – increasing due to adoption of western diet
• Population screening for stool occult blood* in >50y.

Types

Right: proximal, commonly familial

Left: distal, commonly sporadic

Demographics

• Ageing & males slightly more common.
• 1 in 20 people (60-80yo)
• 80% cases sporadic in >50yo
• 20% cases familial <50yo

Risks

• age >50
• Male