Similar to Chronic viral hepatitis.

common with Females (70%), other Autoimmune diseases.

Elevated serum IgG (autoantibody)

subclinical rapid necrosis lead to overt cirrhosis*.

Plenty of Plasma cells*

inflammation of hepatocytes with chronic inflammatory cells

Demographics

• F>M, teenagers + 40-60
• rare

Aetiology

• Auto-immune mediated

Pathophysiology

• Immune-mediated injury to hepatocytes