glomerulosa makes aldosterone (mineralcorticoid)

Zona Fasciculata makes cortisol (glucocorticoid)

• needed in times of stress
• lipid soluble, passes through cell MB to bind with intracellular receptors (almost every cell in body)
• main job to stimulate gluconeogenesis (glucose from AAs and FFAs in liver, as well as fascilitate muscle and adipose tissue into AAs and FFAs
  • free glucose to deal with stress

Zona reticularis makes androgens like dehydroepiandrosterone (testosterone precursor) but not as much as testes

men: testosterone develops male repro tissue and secondary characteristics like facial hair and adams apple

women:growth spurt in development, hair in puberty, sex drive in adulthood

likely stimulated by adrenocorticotropic hormone from pituitary gland

• RAS → decreased K+, increased Na+ and blood volume and pressure
• hypothalamic pituitary adrenal axis