• Adults 40-60y common
• M3 most common
• Neoplastic Blasts in BM, blood, Liver, Spleen
• Anemia, Fever, Bleeding, recurrent infections
• Hepatosplenomegaly moderate
• No significant lymphadenopathy
• Gum hypertrophy

large round blast cells (myeloblasts) with more cytoplasm with granules and Auer rods

AML - M4 (myelomonocytic)

some cells with pink cytoplasm (myeloblasts) and blue cytoplasm (monoblasts)

AML-M7 (megakaryoblastic)

Blasts, abnormal megakaryocytes, giant platelets