<aside> 💡 Inflammation/infection of common bile duct

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Demographics: 6-9% gall stone patients. Equally male or female.

Risk Factors:

• gall stones
• Fat, Female, Forty, Fair, Fertile
• increased age
• rapid weight change
• pregnancy
• Oral contraceptives
• Disorders of bile metabolism & Hyperlipidemias.
• Diabetes

Pathophysiology

• Usually following stones, pancreatitis or ERCP.
• Biliary tract obstruction → bile stasis with increased intraductal pressure → bacterial translocation into the bile ducts → bacterial infection ascends the biliary tract (even into the hepatic ducts) by acute inflammatory cells.

Clinical Features

• Charcot’s Triad/ Reynold’s Pentad
• Abdominal pain (RUQ)
• Fever